Jacob Nagel on the U.S.-Israel War With Iran:
Threats, Strategy, and an Unprecedented Alliance

Prof. Jacob Nagel is a brigadier general (res.) and former acting national security adviser and head of Israel’s National Security Council. He has twice chaired government-appointed Nagel Committees, including the most recent commission established after the October 7 Hamas attack, which delivered strategic and budgetary recommendations to Prime Minister Benjamin Netanyahu on the IDF’s force buildup and long-term defense posture. A key figure behind Israel’s decision to develop the Iron Dome missile defense system, he is currently a professor at the Technion, where he heads the Center for Security Science and Technology and leads advanced defense research initiatives.

In a candid webinar held nine days after the war with Iran began, Brig. Gen. (res.) Prof. Jacob Nagel offered a sobering assessment, outlining what he described as the regime’s core threats, Israel’s military and intelligence achievements, and the cooperation between Israel and the United States.

Nagel began by defining what he called the four central threats posed by Iran — not only to Israel, but to the entire Middle East, the U.S., and the wider world. “The four main threats are, of course, the nuclear capability; ballistic missiles — including, in the future, intercontinental ballistic missiles; UAVs, drones, and cruise missiles; and continuous terror support by the Iranian regime,” he said. A fifth danger, he added, is “the threat of depressing the Iranian people,” as the regime diverts national wealth away from its citizens and toward military aggression and terror proxies.

At the heart of Nagel’s analysis was the conviction that military action alone is insufficient if the regime itself remains in place. “If the regime stays, after we finish this round, we’ll have to do it again,” he warned. “Maybe not in eight months — maybe in 18 months — but we’ll have to do it again.” For Nagel, success must be measured not only by battlefield achievements but by whether those gains endure.

He acknowledged that there are nuanced differences between Israeli and American leadership styles but stressed that strategic alignment remains firm. “The cooperation between Israel and the United States is unprecedented,” Nagel emphasized, spanning intelligence sharing, operational planning, technology, and logistics.

Nagel pointed to Iran’s energy sector as a central vulnerability. Oil and gas revenues, he noted, fund the regime’s military ambitions and terror activities. “Instead of taking this money for their people and making Iran one of the most flourishing countries in the world, they are making it one of the poorest and one of the worst places to live,” he said. Decisions around whether and how deeply to target Iran’s economic infrastructure are complex, but potentially transformative.

Reflecting on the opening days of the war, Nagel described what he called three major achievements thus far. The first was operational capability: air power, intelligence, space technology, communications, and logistical support working in concert. The second was political and international coordination, particularly the deepening partnership between Jerusalem and Washington. The third, and in his view most consequential, was intelligence superiority.

“It’s not magic,” Nagel said of Israel’s intelligence achievements. “It’s 10, 15, sometimes 20 years of very specific work.” Thousands of people, he explained, labor behind the scenes to ensure readiness long before conflict erupts. Iran, he argued, failed to grasp the depth of that capability.

“Israel surprised Iran,” he said. “They learned a lot about technology, but they didn’t learn about our intelligence superiority.”

BRIG. GEN (RES.) PROF. JACOB NAGEL

Nagel also highlighted the Technion’s central role in underpinning Israel’s technological edge. Many of the systems deployed today, he noted, began development more than a decade ago and were advanced by Technion alumni working across Israel’s defense and technology sectors. “I’ll be humble,” he said, “but I know that about 80% of all defense technologies were developed by Technion graduates.”

From air-defense systems such as Iron Dome, David’s Sling, and Arrow to emerging laser technology, Nagel stressed that innovation saves lives. “People said Iron Dome would never work,” he recalled. “It works. It saves lives.”

On the diplomatic front, Nagel described constant, high-level coordination between Israeli and American leaders, underscoring the depth of consultation shaping decisions on both strategy and timing. While not willing to elaborate, Nagel also mentioned implicit messages being sent to China, Russia, and North Korea, and the strategic importance of Taiwan.

While much of his focus was on Iran, Nagel also turned briefly to Lebanon, arguing that Hezbollah’s actions have backfired strategically. “If I were an investor looking for ROI,” he said, “the worst investment Iran ever made is in its terror organizations.”

Hezbollah’s failure to decisively aid Iran during last June’s 12‑day conflict, he suggested, altered regional calculations and opened new — if fragile — possibilities for change. By entering the war now, Hezbollah “dug themselves into a deep hole,” he said, giving Israel “the legitimacy to attack deeply into Lebanon.” As a result, Lebanon’s prime minister, for the first time in the country’s history, appealed to Europe and the U.S. to help broker direct peace negotiations with Israel.

Nagel closed with a stark reminder. Iran’s leadership, he believes, is unlikely to surrender voluntarily.

“Only the people of Iran can take the country from them… and they can’t do it alone.”

Whether that moment comes soon or far later remains uncertain, but for Israel and its allies, preparation, unity, and long-term resolve are essential.

Hear from Brig. Gen (res.) Prof. Jacob Nagel directly in this webinar recording.

Soon after the attacks on Israel on October 7, 2023, N.M. was called to the south to help secure the kibbutzim and other communities near the Gaza border, and to rescue those who may have been wounded or hiding in fear. The operation was the nation’s top priority. For N. it was the start of what he calls “a second reality.”

“Since that day, every person in Israel has had to mix normal life with war, and I am no different.” He was both a reserve combat soldier, who served more than 250 days on the front, and a Technion computer science undergrad — in that order. “From the quiet of the classroom I suddenly found myself back in uniform fighting in Gaza,” he said.

His first mission was to clear the southern communities of Hamas, to bring back control and a sense of security for the civilians who lived there. “We moved house by house, making sure there were no more terrorists and that people could be evacuated or return safely.”

But as he walked through the ruins of burnt kibbutzim and bullet-riddled cars, he thought about the victims: “What did they feel? What were they going through in those moments when it all happened? You look at their belongings and try to guess, ‘Who is this family whose table is set for the holiday?’ You look at that table and pray that the army managed to reach the house before the enemy did.”

Later, when Hamas was pushed back and the situation was more stable, N. and his unit helped the IDF prepare for the ground invasion in Gaza. This meant fighting in several hot spots to ensure Israel’s soldiers could move as safely as possible. “For me, this period was about doing everything I could to protect my country and the people who live here.”

Even those not in uniform experienced fear and hardships. His partner stayed home, “but she went through a lot of loneliness, worry, and a strong feeling that she had no control over what was happening,” he said. “Of course, she was also afraid to lose me.”

Soldiers in his unit were given only a few minutes every few days to talk with their family, and these calls were often quite emotional. N. recalled struggling to sound calm on the phone when war was exploding around him. “When I think about the impact of the war, I see not only the soldiers at the front, but also the families who stand behind us and pay a very heavy price in silence.”

All the while, N. felt divided between his academics and the reality of war. “The Technion became a kind of ‘second reality,’ a picture of normal life inside the chaos,” he said. Taking books with him to the front, he said, “I tried to stay connected to my future by studying in short breaks. It was a way to hold on to normal life and to the future I am building.”

Returning to campus also was not easy. “Life resumed. Students filled the corridors, the coffee shops were busy, exams returned to the calendar. But inside, I carried memories, worries, and the names of friends who were still in uniform or who did not come back.”

The Technion stood by him as it did for all returning soldiers, making special adjustments such as providing extra exam dates, help with catching up on material he missed, and access to recordings of lectures.

“I never felt that I was left alone to choose between serving my country and pursuing my education.”

In Israel, serving in the military is a lifelong commitment. N. has learned to integrate its challenges into the whole of his life — and is hopeful. “You learn to tell the people you love that you love them, and how important they are to you … And to not lose faith that a better future is waiting,” he said.

“Continuing my degree is another way to protect and strengthen Israel, this time with knowledge and innovation instead of a rifle.”

In 2011, Cornell entered into an academic partnership with the Technion — Israel Institute of Technology to compete for an ambitious goal: build an innovative New York City campus to educate a new generation of tech leaders, conduct breakthrough research and development, inspire startups and propel the city to becoming a global hub for the tech industry. Beating national competitors in the bidding process, Cornell and the Technion won the opportunity to create Cornell Tech on Roosevelt Island. Without the Technion, there would be no Cornell Tech.

Nearly 15 years later, Cornell Tech has educated more than 2,700 students and undertaken groundbreaking research on AI and other new technologies.

Critical to this mission is the Joan and Irwin Jacobs Technion-Cornell Institute, created through the unique academic partnership between Cornell and the Technion without a financial obligation from either university to the other. The Jacobs Institute brings together engineers, computer scientists, designers, clinicians and entrepreneurs to develop new technologies, launch startups and generate real-world impact through three research hubs focused on health, media and urban challenges. As is the case at most American universities, all of this research is supported through private philanthropy and competitive grants from U.S. government agencies. At the Health Tech Hub, faculty and students are building machine-learning systems that predict disease progression and assist clinicians with diagnosis and treatment, particularly in areas like cardiology, radiology and emergency care. In the Connective Media Hub, researchers study how digital platforms shape the way information spreads, communities form and public conversations evolve. Within the Urban Tech Hub, researchers explore how advanced data science can improve infrastructure — from housing and transportation to energy systems and climate resilience. Through programs like the Urban Innovation Fellows initiative, researchers work directly with agencies across New York City on challenges ranging from sanitation and procurement to transportation and housing policy.

Belgian-born Technion scientist Dr. Katrien Vandoorne leads research tracking inflammation in the body and says Israel’s collaborative science culture and wartime resilience convinced her to build her lab and raise her family here

When Dr. Katrien Vandoorne first arrived in Israel to pursue her PhD at the Weizmann Institute of Science, she was struck by something that went far beyond laboratories and research facilities. “The people were very collaborative and warm and inspiring,” she recalled. “The science was really great for me, but also the Mediterranean climate, the food, all those things.”

Originally from Belgium, Vandoorne said the country’s scientific culture felt very different from the academic environment she had known in Europe. “In Belgium it’s very hierarchical,” she said. “The professor is very high up, and you should always be very polite and never question anything that is written in the book.”

How did you find Israel’s scientific culture in contrast?
“What I really like about Israel is that, as a master’s student, you can question the whole theory of your professor, and there is no problem with that,” she said. “Your professor will actually like it that the student is engaged and wants to make your theory fall.”

For Vandoorne, that openness was transformative. “No one will ever say, ‘That’s a stupid question,’” she said. “Everybody will say, ‘Hey, that’s a good question,’ and take it as a sport.” She believes this atmosphere encourages creativity and innovation. “The young people, they’re the ones with the, maybe, crazy ideas, but maybe also really solving things that the previous generations couldn’t solve.”

Building a life in Israel

Although Vandoorne later had opportunities to work in Europe and the United States, she and her family ultimately decided to build their future in Israel. “It was really a package deal,” she said. Her husband, an Israeli, had long hoped to return. But Vandoorne said the decision was not only personal. “For me it was really the scientific culture and the unique combination of very good science that wants to make an impact and solve problems, together with a really human environment,” she said.

Dr. Katrien Vandoorne
Dr. Vandoorne having breakfast with her students on the grass next to the faculty building: coffee, ideas, and a little team-buildin (Photo: Private album)

Family considerations also played a central role. The couple moved to Israel in the summer of 2018 with their three young children. “They were 3, 5 and 7,” she said. Starting over in a new country while raising a family was not simple. “Becoming an immigrant means that you have to learn the language, find new friends and also professionally grow,” she said. “It’s been a journey.”

Despite the challenges, she says the experience has been enriching. “Instead of making myself smaller by being only an immigrant, I expanded myself by learning Hebrew and also being part of the Israeli culture,” she said.

Mapping inflammation in the body

Today Vandoorne is head of theIn Vivo Multi-Scale Imaging Lab at the Technion’s Faculty of Biomedical Engineering in Haifa. Before joining the Technion, she worked at leading research institutions in Europe and the United States, including Eindhoven University of Technology in the Netherlands, and conducted research at the Weizmann Institute of Science, where she completed her PhD.

Her team studies how inflammation spreads through the body and how immune cells travel between organs. “When the body faces any stress like infection, chronic disease or heart attack, the immune system is activated,” she explained. “Most of these immune cells come from the bone marrow. It’s like a factory inside the bones where blood and immune cells are produced.” Her work focuses on how inflammation contributes to diseases such as heart disease, diabetes and neurological disorders, conditions in which the immune system plays a key role.

Dr. Katrien Vandoorne

Using advanced imaging technologies including MRI, PET-CT and intravital microscopy, her team tracks immune cells as they move from the bone marrow through the bloodstream to organs such as the heart and brain. “Our goal is really to visualize these inflammatory processes so we can measure them, monitor them and ultimately also treat them,” she said. “Or even diagnose them earlier and be more precise with therapies.”

Vandoorne’s work sits at the intersection of biology, medicine and engineering, reflecting the Technion’s approach of combining technological innovation with medical research.

A unique research ecosystem

Vandoorne says the Technion’s strength lies in its ability to bridge engineering and medicine. “It combines engineers on the technical side and clinicians on the medicine side,” she said. “You have Rambam Hospital, a great medical school and all the engineers needed to solve problems.” Biomedical engineers often stand at the intersection of those disciplines. “We’re really trying to work on real-world problems,” she said.

Dr. Katrien Vandoorne

Beyond infrastructure, she credits the university’s collaborative atmosphere. “It’s a very warm human environment,” she said. “Everybody is open and supporting. Whatever question I have, people are trying to help.”

Life and work during war

Like many Israelis, Vandoorne’s daily life has also been shaped by the ongoing war. “The war has been a rough pill to swallow,” she said. Without extended family nearby and with many international friends leaving Israel after the October 7 attacks, the experience has been emotionally challenging. “I built up a whole network of friends and most of them left,” she said. “It was very confronting for me to need to start it up again.”

Yet she says both her children and her students have helped her navigate the uncertainty. “My children teach me the most about how to deal with it,” she said. “I worry about them and they tell me not to. They say they are fine.” Her lab community has also provided support. “For me our faculty feels like a small family,” she said. “Everybody is really part of the community.”

Dr. Katrien Vandoorne

During periods of heavy rocket fire from Hezbollah in northern Israel, staff and students often gathered in a large underground shelter inside their building. “We were just all down there trying to ground ourselves by talking science in the shelter while bombs were falling,” she said. “After everything stops everybody gives a hug and we go back up and continue our day.”

Believing in Israel’s scientific future

Despite the difficulties, Vandoorne remains optimistic about Israel’s future in science and innovation. “I think if anywhere there’s going to be biomedical innovation, it’s going to be here,” she said. Part of that belief comes from what she sees as a national resilience. “We are not afraid of anything,” she said. “That lack of fear stops many people in other countries from innovating.”

Dr. Katrien Vandoorne

Facing constant challenges can also fuel creativity, she said. “If you are in a country where everything is good and everything is fine, you don’t want to take a challenge,” she said. “Here we deal with challenges every day.”

For Vandoorne, that spirit continues to shape both her research and her life in Israel. “It really feels like a place where people want to solve problems and help each other,” she said. “That’s why I want to stay.”

Prof. Katrien Vandoorne is head of the In Vivo Multiscale Imaging Lab in the Faculty of Biomedical Engineering in the Technion – Israel Institute of Technology.

As the world is told about the war between Iran, Israel and the United States in the language of strategy and security, my prism is memory. For many, this is geopolitics. For me, it never really is.

All my grandparents were Persian Jews. They left their homes when the country they had known most of their lives had become home no longer. They felt unsafe under a regime that was fast becoming more rigid and fundamentalist.

They left behind property, wealth, community and family. Some relatives who stayed were imprisoned. Many others were killed. In our family, those stories are not told as political history, they are told as personal experience.

Before the Islamic Revolution in 1979, Iran back then was a rapidly modernising country, vibrant and sophisticated with an incredibly rich culture. Under the rule of the Shah, it blended ancient heritage with a booming, Western-influenced urban culture – and the Jews were protected.

For centuries, Jews in Persia contributed to its society in many meaningful ways. My own family, from Mashhad, were educated, entrepreneurial and deeply connected to the people around them. The shift did not happen overnight. It rarely does, but as Islamic fundamentalism hardened into state power, Jewish life became increasingly precarious. What once felt like belonging, became uncertainty, and then fear. That change shaped the course of my family’s life, and it still echoes.

They were lucky and managed to leave the country before the current evil regime took power. They move to Israel, the US and the UK.

I was meant to be in Israel this week on a Technion UK solidarity visit. Cancelling the trip was not an easy decision. It felt heavy, and even disloyal. Yet whether I am in Israel or in London, what is unfolding does not feel far away. It feels familiar in ways that are too difficult to explain to those who do not carry a similar history.

As CEO of Technion UK, I proudly represent Israel’s oldest university and one of its leading scientific and technological institutions. Technion graduates have played a central and leading role in many areas including developing nearly all of Israel’s defence systems that protect Israel’s citizens of every background; Jewish, Christian, Muslim, Druze and Bedouin. But beyond the technology is something more enduring: a determination to keep building and contributing to the country and the world, even under threat.

When I spend time with members of the Persian Jewish community in London, I do not hear rage. I hear deep sadness. There is grief for a country they once loved that no longer exists. Their hope for change is not driven by vengeance. It is shaped by longing and the memory of what once was.

Behind the headlines are so many families like mine: 150,000 Jews shaped by exile, resilience and memory. That is not ancient history. It sits within living memory, around Shabbat tables, in the stories grandparents tell our children.

Purim teaches us that Jewish history has never moved in a straight line. There have been moments of threat, moments of reversal and moments of renewal. Remembering that is simply part of our inheritance.

For me, this moment is not only about strategy or security. It is about responsibility, to those who came before us, and to those who will come after. That is why it feels so personal.

Ali Ayoub told the Globes Putting the North at the Center Conference that Nvidia does not see the north as a periphery but as the center of the AI revolution.

“I was born and raised in the (Galilee) village of Majd al-Krum and was infatuated by the field of technology from an early age. I remember my father buying us a computer, which was not a given. I shared the computer with my brothers,” Nvidia VP software engineering Ali Ayoub told Globes technology editor Assaf Gilead at the Globes Putting the North at the Center Conference held in cooperation with Bank Leumi and Strauss Group.

Nvidia VP Ali Ayoub credit: Cadya Levy

Ayoub spoke about AI and if it will replace engineers and juniors, how to hire employees in the North, how to integrate Arab society into tech professions, Nvidia’s cooperation with academia, and how he reached his current position at Nvidia. Ayoub’s path to Nvidia VP included several stages: he earned a degree in computer engineering at the Technion – Israel Institute of Technology, worked at Mellanox, moved to the US where he worked at Google and founded a startup, and after 10 years he returned to Israel and Mellanox, and remained there even after the acquisition of Nvidia. At the US chip giant, he founded the DOCA feature group and today manages hundreds of employees at Nvidia in Israel and around the world. He is also cofounder of the HAAT food delivery company.

When asked why he chose to return to Israel, he replied: “People usually ask why I left the center of the country and came to the north. I left the center of the world, Silicon Valley, and returned to the north. This is home. In high-tech, they always talk about the importance of work-life balance, the north is ‘life’, and also being close to family and Nvidia is ‘work’. For me, the stars aligned and looking back, this is one of the best decisions I made.”

Nvidia is to build a large development center in Kiryat Tivon over the next decade for 8,000-10,000 employees. Why in the north and specifically in Kiryat Tivon?

“The north has excellent human capital, and tech companies are really looking for the best. In the north, first of all, there are very good universities. Also in general, if you want to find good people, it is worth looking where others are less likely to look. In Nvidia’s eyes, the north is a place with excellent human capital and a place for growth, and it is no coincidence that they chose Tivon. From our point of view, there is raw material here and it is full of talent that we would be very happy to recruit to Nvidia to reach even further and greater growth. In my opinion, not only is there talent here, but also untapped talent here.”

Can you expand about Nvidia’s activities in Israel?

“Nvidia Israel, which employs 5,000, is the company’s biggest branch worldwide outside the US. The employees are the nervous system of data centers. They focus on the field of networking and the transformation of AI. Nvidia makes the GPU (graphics processing unit), the AI engine, and if hundreds of GPUs were once enough to build AI data centers, today thousands are needed. They must be connected to a very fast network, and this is where Nvidia Israel comes in. We provide these fast networks. This is the beating heart of the AI revolution not only in Israel, but around the world.”

How do you hire employees in the North?

“Firstly, you have to believe that they exist, look for them and then find them. It’s a matter of cause and effect. In all kinds of jobs, not just in high-tech, there is a lot of stress on the balance between work and home. The North brings the home part and we have to work on the work part. So, companies must set up branches here and focus on here and create the opportunity to work in quality jobs. This is, in my opinion, the number one element that will keep people here. Nvidia does not see the North as a periphery but sees it as the center of the AI revolution, and you have to believe in it and see it and when you look, you find it.”

Are you working with universities in order to build a pool of employees in the future?

“For us, universities are not just a collaboration, but complement us. This is not done as a favor to the universities, but we want to bring the best to us. Personally, every two months, there is a high school or school that comes to visit. It starts even before the universities.”

Ayoub spoke about collaboration with the universities: “We work very closely with them. This is reflected in job fairs, and we have a program that provides AI tools to lecturers and students, and this brings us very close together.”

On the change required in universities and the integration of AI tools, he said, “I think universities are changing. They also turn to us and we suggest how to change the syllabus and courses. The juniors and students we hire do an excellent job and integrate into AI very quickly. We take people when they have the basic tools, and we do the education and use of AI tools within the company.”

On the difficulty of juniors finding tech jobs, he said, “We hire a lot of juniors and we are at the center of the AI revolution that will require more work. We need to hire people. The reason we are doing this is because we believe in juniors and do not believe that AI will replace them.”

“Whoever doesn’t use AI will get left behind”

You are Nvidia VP software engineering, and this is the area most vulnerable to the impact of AI. There are companies where employees and programmers have not programmed for six months. Do you believe that the programmer will be replaced by AI?

“Not at all. AI will not replace the engineer, but any engineer who does not use AI will be replaced by another engineer who does use it. Almost every engineer at Nvidia uses AI. Things that take weeks to do alone, today can be done in days or hours. It is such an essential tool that anyone who does not use it will be left behind. AI will certainly create new jobs for those who look at it from the right angle.”

What would you recommend to your young children when they grow up to study: software or electrical engineering?

“You cannot do one without the other. I studied software and work in it, but the software I make is software that complements the hardware. The hardware is the body and the software is the mind. You cannot have a body without a mind and vice versa. They complement each other.”

You have previously told me that when you were growing up, your family took it very hard that you went to study computer engineering.

“My parents wanted me to be a doctor, maybe to this day,” laughs Ayoub. “I remember when I wanted to enroll in school, there was the option to give two majors. But I asserted myself, and I only registered the first major.”

How has Arab society changed in recent years and how easy is it for young people to integrate into the tech industry?

“We see them at the Technion, but many give up after their degree and go do other things. But still, almost 16% of the students today in technology subjects are from Arab society. At the Technion, close to 20% of students are Arab, which is very close to the percentage of the population. 50% of Arab students are female students, and this representation we are very proud of. Tech companies are looking for diversity and we see it as a blessing and something good that brings better products.”

Ayoub stresses that more work is needed because there are not many entrepreneurs from Arab society: “Today there is more openness and exposure to technology and we need more role models to say ‘When I grow up, I will be a tech professional’. I think it is happening, but we need to give it more push.”

Full disclosure: The conference was held in cooperation with Bank Leumi and Strauss Group, and sponsored by Aura Investments, Tel-Hai Academic College, Propdo, and with the participation of Netivei Israel National Transport Infrastructure Co.

Technion and top US universities unveil implantable ‘living pancreas’ that senses glucose, produces insulin and evades immune response, paving the way for self-regulating, long-term diabetes treatment without daily injections

A multinational research team led by an Israeli engineer and involving top U.S. universities has unveiled a pioneering implantable device that could someday eliminate the need for daily insulin injections for people with diabetes.

The study, published Jan. 28 in Science Translational Medicine, describes a living, cell‑based implant that functions as an autonomous “artificial pancreas.” Once placed in the body, the device continuously monitors blood glucose levels, produces insulin internally and releases exactly what the body needs — without external pumps, injections or patient intervention.

The breakthrough centers on a novel protective technology researchers call a “crystalline shield”, engineered to prevent the body’s immune system from rejecting the implant — a major hurdle that has stymied cell‑based therapies for decades. The shield allows the implant to operate reliably for years.

Tests in mice showed effective long‑term glucose regulation, and studies in non‑human primates confirmed that the cells inside the implant remain viable and functional, the researchers said. Those results, they added, provide strong support for future clinical testing in humans.

The work was led by Assistant Professor Shady Farah of the Technion — Israel Institute of Technology’s Faculty of Chemical Engineering, in collaboration with scientists at the Massachusetts Institute of Technology, Harvard University, Johns Hopkins University and the University of Massachusetts. The collaboration traces back to Farah’s postdoctoral work beginning in 2018 at MIT and Boston Children’s Hospital/Harvard Medical School, under tissue‑engineering pioneers including Robert Langer, a co‑founder of Moderna.

Assistant Professor Shady Farah
Assistant Professor Shady Farah

Farah’s co‑first authors on the paper are Matthew Bochenek of MIT and Joshua Doloff of Johns Hopkins. Other contributors include Technion researchers Dr. Merna Shaheen‑Mualim and former master’s students Neta Kutner and Edward Odeh, who also helped adapt the work for publication.

While the initial focus is on diabetes, the team emphasized that the platform could one day be adapted to deliver other biologic therapies continuously, offering a new approach to chronic conditions such as hemophilia and other metabolic or genetic diseases.

If successfully translated into human treatment, experts say the technology could reshape the management of chronic illness by replacing lifelong drug regimens with self‑regulated, living therapeutics working continuously inside the body.

The special collaboration will help advance Israeli innovation, energy security, and civil aviation. After concluding the project feasibility study, Boeing and the Technion announce advancement to the next stage of practical development

January 27, 2026 – Dr. Brendan Nelson, President of Boeing Global, visited the Technion yesterday to mark a milestone in the activities of the Boeing–Technion Innovation Centre for Sustainable Aviation Fuel (SAF) and to launch the implementation phase. This strategic partnership, the Boeing–Technion SAF Innovation Centre, was launched in 2023 to develop sustainable fuels for the aviation industry. According to the project partners, aviation’s long-term growth will be enabled by producing SAF from feedstocks including green hydrogen and carbon dioxide, and the joint centre will advance this process to a level that enables commercial production at a competitive cost.

Also participating in the visit on behalf of Boeing were Boeing Israel President Maj. Gen. (res.) Ido Nehushtan and Haggai Mazursky, Head of the SAF project. The Boeing delegation was welcomed at the Technion by Technion President Prof. Uri Sivan; Vice President for Research Prof. Noam Adir; Vice President for Innovation and Industry Relations Prof. Yuval Garini; and Head of the Centre Prof. Gidi Grader of the Wolfson Faculty of Chemical Engineering.

Dr. Nelson, a physician by training, previously held senior positions in the Australian government, including Member of the Australian Parliament, Minister of Defence, Minister for Education and Science, and Ambassador to Europe. During his visit to the Technion, Nelson said: “In addition to delivering high-quality fuel-efficient airplanes to our customers, Boeing works globally and regionally to enhance energy security, support the growth of the civil aviation industry, and create new economic opportunities through sustainable aviation fuel and other technologies. We are pleased to partner with Technion and other stakeholders in the SAF Innovation Centre to support Israel’s aerospace industry.”

“This is a historic collaboration of national importance for the State of Israel,” said Technion President Prof. Uri Sivan. “The partnership with the global aviation leader, Boeing, is, for us, a vote of confidence in the Technion, its researchers, and our technological capabilities. Through this collaboration, Technion experts are taking on a tremendous mission: to develop technologies for producing clean fuels through sustainable processes, thereby making a significant contribution to aviation—and no less importantly, to human health and the environment. I do not doubt that we will meet this challenge, just as we have met many others over the past hundred years.”

“Boeing has been active in Israel since before the establishment of the State and serves as an important supplier to El Al and the Israeli Air Force,” said Maj. Gen. (res.) Ido Nehushtan, President of Boeing Israel. “Israeli industries are now key suppliers to Boeing, and many Israeli systems are integrated into the company’s products worldwide. Boeing has continued to deepen its research and development ties with academia and industry in Israel, as well as its investments in the high-tech sector.” The President of Boeing Israel added that the collaboration between the Technion and Boeing will pave the way for the development of Israel’s most advanced technologies and capabilities, which will be integrated into future generations of aerospace systems around the world.

The Boeing–Technion partnership was initiated by Boeing and includes partners from across the industry and government in Israel. The Israeli Government has provided measures and financial support to accelerate the Israeli SAF industry, which include Israel’s Ministry of Innovation, Science, and Technology establishing the ISAF research consortium and the Israel Innovation Authority launching SAF-IL which is an incubation program for Israeli start-ups dealing with SAF development.

To lead this groundbreaking vision for the development of SAF, Boeing partnered with Prof. Gidi Grader of the Technion’s Wolfson Faculty of Chemical Engineering to establish the centre, which has now completed its proof-of-concept phase. As part of the partnership, 11 Technion faculty members and dozens of doctoral students from five different faculties are working on various aspects of aviation fuel production, including efficient and competitive manufacturing; theoretical aspects of catalytic reactions and fuel combustion; safety considerations; full life-cycle analysis; and the establishment and operation of an experimental fuel-testing facility at the Technion, which will be only the second of its kind in the world.

The announcement of the Boeing–Technion partnership was originally planned for October 2023. Despite the events of October 7 and the war that followed, the decision was made to continue with the technical work, as Dr. Nelson explained several months later: “We launched this initiative, a project of resilience and innovation in the spirit of the Jewish people and the State of Israel, shortly after the horrific October 7 attack. When I met the Prime Minister a few months earlier, I told him that if there is one country in the world capable of solving civil aviation’s emissions challenge, it is Israel, led by the Technion—the Israeli MIT.”

Now, two years later, following the completion of the initial feasibility phase, senior Boeing executives were presented with the progress achieved to date, and the second phase of the initiative was launched: the development of SAF produced from green hydrogen and carbon dioxide, and the advancement of the process to a level that will enable competitive commercial production.

Prof. Ido Kaminer and Prof. Yehonadav Bekenstein of the Technion have been awarded ERC Proof of Concept (PoC) grants by the European Research Council. The grants are expected to lead to a major leap forward in low-radiation medical imaging and in the precise mapping of biological tissues.

Two young researchers from the Technion have won the prestigious ERC PoC grants from the European Research Council (ERC). Proof of Concept grants are feasibility grants designed to promote the transition from academic research to application and commercialization, including the establishment of a startup company, and are awarded only to researchers who have previously received ERC grants. Grant amount: €150,000 each.

The two recipients are Prof. Ido Kaminer from the Andrew and Erna Viterbi Faculty of Electrical and Computer Engineering and Prof. Yehonadav Bekenstein from the Faculty of Materials Science and Engineering. Both joined the Technion faculty in the same year, 2018, and in 2025 inaugurated a joint interfaculty laboratory: the Quantum Microscopy Lab. This innovative lab is equipped with state-of-the-art microscopes capable of detecting quantum phenomena that cannot be studied by other means. The laboratory, which also includes Dr. Michael Krüger from the Faculty of Physics, was established following the Technion’s success in a call issued by the National Authority for Technological Innovation, with support from the Helen Diller Quantum Center at the Technion.

Prof. Yehonadav Bekenstein, a graduate of the Hebrew University of Jerusalem, joined the Technion faculty after a Rothschild postdoctoral fellowship at the University of California, Berkeley. He is considered a leading scientist in materials discovery, specializing in light-emitting nanomaterials and perovskites  the technology at the heart of the new sensor that earned him the grant. His scientific work has been recognized with a series of prestigious awards, including the Krill Prize for Excellence in Scientific Research and the Goldberg Prize from the Technion.

The grant Prof. Bekenstein received will be used to advance MagicLayer a sensor for a new generation of medical imaging with minimal radiation exposure. The scientifc idea of the developed technology is based on nanocrystals and ultrafast quantum light emission.

3.המעבדה למיקרוסקופיה קוונטית בטכניון. מימין לשמאל : מנהל המעבדה ד"ר קובי כהן, פרופ' עדו קמינר , ד"ר מיכאל קרוגר ופרופ' יהונדב בקנשטיין.
The Quantum Microscopy Laboratory at the Technion. From left to right: Prof. Yehonadav Bekenstein, Dr. Michael Krüger, Prof. Ido Kaminer, and laboratory director Dr. Kobi Cohen

Sensors used in medical imaging are currently limited by their response speed. This relative slowness leads to the loss of valuable information and forces physicians to increase patients’ exposure to radiation. Standard crystals used in industry have reached the limits of their classical physical capabilities and struggle to deliver the field’s “holy grail,” which is a time resolution of 10 picoseconds. This is where the new sensor comes in; it is based on arrays of nanocrystals developed at the Technion. The light emitted from these arrays is correlated and responds significantly faster than existing technologies. The technology is relevant not only to medicine but also to improving electron microscopes and to real-time monitoring of radioactive gases in nuclear facilities. The research team behind the winning proposal includes Dr. Georgy Dosovitskiy, Dr. Rotem Strassberg, and Shai Levy.

Prof. Ido Kaminer, who completed all of his degrees at the Erna and Andrew Viterbi Faculty of Electrical Engineering, returned as a faculty member after a postdoctoral fellowship at MIT. He is a world-renowned scientist in photonics, electron microscopy, light–matter interactions, quantum information processing, and mathematical discoveries using artificial intelligence. His scientific work has earned him numerous honors, including the Stanisław Lem Prize, the Schmidt Science Polymath Award, the Blavatnik Award, the Krill Prize, and election to the Israeli Young Academy.

His new grant will be used to develop Stork – an innovative module that improves the performance of transmission electron microscopes (TEM). These instruments are widely adopted for biological applications as well as semiconductor metrology and inspection. However, their capabilities across both fields are highly limited owing to low contrast, which hinders resolution and throughput. The Stork technology makes it possible to introduce light directly onto the studied specimen, while also efficiently collecting the light emitted from it, thereby enhancing the TEM imaging capabilities dramatically. This paradigm shift in TEM technology will provide unprecedented information for imaging biological tissues and atomic-scale defects in electronic devices. The research team behind the winning proposal includes Dr. Tal Fishman, Dr. Michael Yannai, and Dr. Raphael Dahan, as well as students Marta Rozhenko and Rotem Elimelech.

Researchers at the Technion Faculty of Biology have discovered that a mechanism responsible for breaking down toxic proteins, and known to be involved in the development of Alzheimer’s disease, may actually spread these proteins to neighboring cells, thereby promoting the progression of the disease in the brain

A research group led by Professor Michael Glickman, dean of the Technion’s Faculty of Biology, has uncovered a key mechanism in the development of Alzheimer’s. The mechanism in question identifies toxic proteins and disposes of them. In most cases, harmful proteins are degraded inside the cell. However, the researchers found that in certain situations, the very system meant to eliminate these proteins simply transfers them outside the cell. This discovery may explain how a disease that begins randomly in individual neurons can spread to large regions of the brain.

The study, published in PNAS, was led by Prof. Glickman and postdoctoral researcher Dr. Ajay Wagh. In their article, they describe how brain cells deal with UBB+1, a defective and toxic variant of the protein ubiquitin.

The ubiquitin system is essential for breaking down damaged and dangerous proteins. Ubiquitin helps the body eliminate such proteins. The problem arises when ubiquitin mutates into UBB+1. Instead of protecting the cell, UBB+1 harms it, forming protein aggregates associated with the development of Alzheimer’s disease. In brain cells, this damage is particularly severe because neurons do not divide or regenerate – once a neuron dies, it cannot be replaced. One of the “gatekeepers” that prevents UBB+1 from poisoning brain cells is the protein p62, which is involved in the cellular self-cleaning process known as autophagy. Acting as a smart receptor, p62 recognizes UBB+1 and encloses it in a vesicle that prevents it from causing harm.

Next, one of two things happens: p62 either directs the vesicle to the lysosome, which is the cell’s recycling centre, or secretes it out of the cell into the intercellular brain fluid. The Technion researchers show that the second option may endanger brain tissue. Once the vesicle is expelled into the brain’s extracellular fluid, fragments of the toxic UBB+1 protein may leak into neighboring neurons, thereby accelerating the spread of Alzheimer’s pathology.

According to Prof. Glickman, “We all want someone to take out the trash, but in this case, the cells are dumping their trash on their neighbors. Although this solves an acute problem for the individual cell, it may cause long-term damage to the entire tissue. We believe that uncovering this mechanism will enable, first, early diagnosis of Alzheimer’s disease based on analyses of cerebrospinal and other body fluids, and second, the development of precise, personalized treatments.”

The study was supported by the Israel Science Foundation (ISF) and the European Research Council (ERC).